Abstract

Objective To study the therapeutic effects of EUS-guided biliary drainage (EUS-BD) using a nitinol fully covered self-expandable metal stents in patients with malignant obstructive jaundice after failed ERCP. Methods From January 2016 to January 2018, all patients with malignant obstructive jaundice who failed ERCP underwent EUS-guided biliary drainage using nitinol fully covered self-expandable metal stent at Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine. The operation success rate, liver functional recovery time, complication rate, length of hospital stay and survival time were observed. Results Of 36 patients who underwent EUS-guided biliary drainage, 34 were successfully performed, with 19 through the stomach, and 15 through the duodenum. The operation success rate was 94.4% (34/36). The liver functional recovery time of the 34 patients were 25.8 ± 6.5 days. One patient developed hemobilia and one cholangitis, both improved after conservative treatment. The total complication rate was 5.6% (2/36). The hospital stay and survival time were 21.5 ± 4.7 days and 220.5 ± 54.8 days, respectively. Conclusion EUS-BD using nitinol fully covered self-expandable metal stents was a feasible and effective treatment in patients with malignant biliary obstruction after failed ERCP. Key words: Jaundice, obstructive; Neoplasms; Palliative care; Endoscopic ultrasonography(EUS); Bile duct stent; Biliary drainage

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