EUS-guided aspiration biopsy for gastric lesions with thickened gastric wall

Abstract

Objective To explore the diagnostic value of EUS-guided aspiration biopsy for wall-thickened gastric lesions. Methods A retrospective study was performed in 45 patients who were diagnosed as having thickened gastric wall by EUS examination.Pathological and follow-up results of routine endoscopy and EUS-guided aspiration biopsy were analyzed, with the surgical results and follow-up outcome as the golden standard.The positive rate of routine endoscopy and EUS-guided aspiration biopsy were compared. Results In routine biopsy, gastric cancer was confirmed in 6, lymphoma in 3, dysplasia in 6, Menetrier's disease in 2 and inflammatory changes in 28.EUS-guided aspiration biopsy was conducted in 45 patients, and gastric cancer was confirmed in 18, lymphoma in 5, dysplasia in 4, Menetrier's disease in 2 and inflammatory changes in 16.The final pathological and follow-up results confirmed 21 gastric cancer, 6 lymphoma, 2 dysplasia, 2 Menetrier's disease, other tumors in 4 and inflammatory changes in 10. The accuracy rate of routine biopsy and EUS-guided aspiration biopsy was 51.11%(23/45) and 82.22%(37/45)respectively. Conclusion EUS-guided aspiration biopsy can yield a higher positive rate than endoscopic biopsy. Key words: Endoscopic ultrasonography; Fine needle aspiration; Thickness of gastric wall