Abstract

<i>Artemisia argyi</i> is a well-known medicinal plant which has been used in traditional Chinese medicine for thousands of years. It is usually named Aicao or Aihao in China, and the leaves are processed and applied in moxibustion to treat different kinds of diseases. In order to select the best germplasm resource to grow high quality herbal products, we have compared the HPLC fingerprints profiles of 52 geographically different germplasm resources collected from 17 provinces of China. The results data were processed by similarity and hierarchical clustering analyses. In addition, common patterns of a typical local variety of <i>A. argyi</i> sourced in Henan province are established, and sample similarities were evaluated by selection of 14 typical chromatographic peaks of 10 samples and are found to vary between 0.664 and 0.969. The results show that the HPLC fngerprint analysis and quantitative analysis is a powerful tool to identify and control the quality of fresh <i>A. argyi</i> and related products. In addition, the content of a major secondary metabolite in the leaves of <i>A. argyi</i> known as eupatilin, which is a flavone with numerous bioactivities such as anticancer, anti-inflammation and anti ulcer has been determined for all the 52 samples by HPLC-DAD. The results provided great scientific basis for the research and development of the herb as popular products for the health care of human beings.

Highlights

  • The medicinal plant Artemisia argyi Levl. et Vant. is quite famous and popular in China and worldwide [1]. (Figure 1)

  • The leaves of A. argyi were chosen because the moxibustion application of this plant is leaves, and volatile compounds contribute to most of the functions of moxibustion

  • Secondary metabolites were often found in glandular trichomes on the leaves [18]

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Summary

Introduction

The medicinal plant Artemisia argyi Levl. et Vant. is quite famous and popular in China and worldwide [1]. (Figure 1). Is quite famous and popular in China and worldwide [1]. It is edible and can be used to make pastries, breads, dumplings, cakes, and can be mixed with rice or processed into tea or wine. It has been used as an air purifier and a mosquito repellent [2]. There are four famous A. argyi recorded in China, namely northern A. argyi (produced in Tangyin, Henan), Hai

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