Eugenol-based molecularly imprinted membrane synthesis for glucose selective transport

Abstract

In the body of patients with Diabetes Mellitus (DM), there is a lack of insulin because the body cannot transfer glucose into the cells causing blood sugar (glucose) cannot be converted into glycogen so that the level of glucose in the blood rises. Indonesia is a country that has various types of plants, one of which is cloves which contain 80-90% eugenol. Eugenol is an organic compound having three functional groups, namely allyl, hydroxy, and methoxy groups, which are very selectively used as mixed membrane materials. Molecularly Imprinted Membrane (MIM) transport offers glucose selective transport technology flat as a candidate for hemodialysis membranes. MIM-Glucose has better effectiveness and selectivity for glucose than NIM (Non-Imprinted Membrane). The results obtained from the synthesis of eugenol into polyeugenol (PE) were 99%. Analysis of contacting PE with 7500 ppm glucose using FTIR where there is an increase in the intensity of the OH group at a wavenumber of 3537 cm-1 which indicates contact has occurred when it is used to bind to polysulfone and PEG 6000 the intensity of the OH group becomes very decreased in MIM-Glucose and NIM. MIM transport and selectivity are affected by pore size, porosity, hydrophilicity, glucose concentration in the feed phase. Transport and glucose selectivity using MIM is better than NIM.