Abstract

Eugenia Uniflora Active Fraction Inhibits Dalton Lymphoma Ascites in Swiss Albino Mice - An in Vivo Study - written by S. Syama , Dr. M.S Latha published on 2019/12/23 download full article with reference data and citations

Highlights

  • Cancer is the uncontrolled splitting of cells within a fraction

  • Results of the short term anticancer activity of Eugenia uniflora using Trypan blue method revealed that EF18 fraction exhibited cytotoxic activity against the Dalton’s lymphoma ascites cells.EF18 inhibited the growth of Daltons Lymphoma Ascites (DLA) cell lines in a dose-dependent manner

  • In the current In vivo study animal groups treated with EF18 especially its higher dose reduced the tumor volume when compared to the untreated DLA group

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Summary

Introduction

Cancer is the uncontrolled splitting of cells within a fraction. The cancer cells attack and demolish normal cells. Derived drugs, chemotherapy, radiation are very common treatments of cancer. Both chemotherapy and radiation are lethal and toxic to normal cells. Most of these currently used anti- cancer drugs are harmful to the human health. New plant derived drugs are needed since they have fewer side effects [3].Cancer executes a serious burden on public health issues [4]. Plants exhibited a major role in the history of cancer treatment. Cancer occurs as a result of uncontrolled bioenergetics metabolism and by the overexpression of proto-oncogenes which in turn causes the liberalized cellular response. Cancer chemoprevention is known as anti-carcinogenesis [8]. Causative agents of cancer include smoking, imbalances in the diet, hormonal imbalance, and some of the chronic inflammations [9]

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