Abstract

A new pholoroglucinol derivative named eucalyptone G (4) together with nine known compounds (1-3, 5-10) were isolated for the first time from the ethyl acetate fraction of the bark of small twigs of Eucalyptus globulus Labill. Their chemical structures were established on the basis of physical, chemical and spectroscopic methods 1D ( 1 H and 13 C) NMR and 2D (COSY, HMQC and HMBC) NMR in addition to mass spectrometry and comparison with literature data. Eucalyptone G displayed antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Escherichia coli.

Highlights

  • Eucalyptus L’Heritier (Myrtaceae) is one of the world’s most important and most widely planted genera

  • In the present work we report the isolation and structure elucidation of one new phloroglucinol derivative named eucalyptone G, together with nine known compounds

  • Positive-ion electron spray ionization mass spectra (ESI-MS) were performed on a Thermofinnigan LCQ DECA mass spectrometer coupled to an Agilent 1100

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Summary

Introduction

Eucalyptus L’Heritier (Myrtaceae) is one of the world’s most important and most widely planted genera. The methanolic extract of the powdered bark of Eucalyptus globulus Labill. The ethyl acetate fraction afforded one new phloroglucinol derivative named eucalyptone G (4) and nine known compounds (1-3, 5-10).

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