Abstract
We present an experimental study on 49 New Zeland white rabbits. Two groups were made. The first group comprised 14 animals in which a bone cavity was made at the metaphyseal level of femur and tibia at the same operation, without any cavity filling. The 35 animals from the second group were operated on like group I, but in all these animals the cavities were filled with two plaster of Paris pellets impregnated in gentamicin. Biochemical, radiographic and histologic analysis was done on all the animals from the moment of the operation until the animals were killed. The statistical comparison was carried out by using Wilcoxon and student t Tests, considering significant values p < 0.05. We can see complete absorption of the plaster of paris pellets. Cavitary osteogenesis was produced in bone defects.
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