Etiopathological and diagnostic study of Margavaranajanya Hridroga w.s.r. to Coronary Artery Disease - An Observational Study

Abstract

The incidence of cardiac diseases is increasing at an alarming rate in our society due to sedentary lifestyle as an impact of western culture. In India, many studies have reported increasing coronary artery disease incidence over 60 years. One in 4 deaths in India are due to coronary artery disease. So thorough understanding of pathogenesis of this disease is very important. Ayurveda literature elaborates multiple maladies related to heart under Hridroga. Margavarana is a unique pathology explained in our classics. Various dietary, behavioural, psychological factors contribute to morbid accumulation of Kapha and Medas leading to Shonita Abhishyandana. Further morbid state of Shonita Abhishyandana by Upalepa of Dhamani culminates in development of Dhamani Prathicchaya. Eventually due to Siraaja Granthi Dhamani Prathichhaya ends up in Margavarna and is the leading pathology of Hridroga. In the realm of conventional medicine, it is said that sedentary life style is the major cause of morbid accumulation of fat in the body leading to metabolic syndrome. It is characterised by dyslipidemia which in turn leading to atherosclerosis. Atherosclerosis predisposes the thromboembolism and complete obliteration of blood circulation within the vessel. Hence, in the present study an endeavour is made to corelate the concept of Coronary artery disease and its ill effects with the classical reference regarding the concept of Margavarana pathology occurring in the Hridaya causing Margavaranajanya Hridroga and also its diagnosis through the modern tools.