Etiology of severe pneumonia in children in Wenzhou

Abstract

Objective To investigate and analys the etiology of severe pneumonia in children in Wenzhou.Methods A retrospective analysis was performed in pediatric inpatients with severe pneumonia in our hospital from 2008to 2009. All the clinical and etiologic records were collected and analyzed. Results 110 patients were diagnosed as severe pneumonia,and the male-female ratio is 2.93:1. The age of patients ranged from 1 month to 15 years, in which patients younger than 2 years old accounted for 80.91％(89/110). There were 76 patients whose pathogens were identified and 109 strains pathogens were found, in which bacterial pathogens were 50 strains of bacteria(45.87％), 42 strains of virus(38.53％), 13 strains of mycoplasma(11.93％). In 50 strains of bacteria, 38 attains (76.00％) were gram-negative, 12 strains (24.00％) were gram-positive. The predominant bacterial were Klebsiella pneumoniae, Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Burkholderia cepacia. 42 strains of virus were detected, in which 26 strains (61.90％) were respiratory syncytial viruses(RSV), others were influenza virus A, adenovirus, parainfluenza virus Ⅰ and Ⅲ. 24 patients younger than 6 months old suffered from severe pneumonia with RSV infection, which accounted for 38.71％ (24/62) in this age group of severe pneurnonia cases. 13 patients were infected with mycoplasma,in which 9 cases (69.23％) aged from 2 to 5 years old. There was no significant differences amony the rates of cases infected by different pathogeny in different seasons ( x2 = 15.31, P ＞ 0. 05). Conclusions Severe pneumonia in children predominantly occur in patient younger than 2 years old in Wenzhou. Gram-negative bacteria is a crucial pathogen of severe pneumonia in children. RSV is a major pathogens of severe pneumonia in infant younger than 6 months old. Severe pneumonia caused by mycoplasrna predominantly occurs in children aged 2-5 years old. Key words: Pneumonia; Etiology; Children