Abstract

Aim: In this study, the reason of the acute renal failure (ARF) clinic features and results of it has examined as retrospectively. Methods: In this study, the etiology, clinical features and outcome of acute renal failure (ARF) evaluted retrospectively in the Anatolian region of Turkey. Above mentioned features were examined retrospectively in 36 ARF cases (mean age 31.6±6.8, range 17-46), related to pregnancy between 1997 and 2001. Results: The ARF has developed approximately on the 30 th gestational week. The reasons of ARF were; HELLP Syndrome and preclampsia (44%) in 16 cases, postpartum hemorrhage in 7 cases (19%), placenta detachment in 5 cases (14%), septic or spontaneous abortion in 5 cases (14%), and eclampsia in 3 cases. The 5 cases related to the abortion were seen (14%) in the first trimester and others were developed (86%) in the third trimester or postpartum period. In 9 cases (25%) there were intrauterine dead. In 24 of the ARF cases (67%) had hypertension at the time of the diagnosis whereas six cases (17%) had hypotension related to the vaginal bleeding. All cases had oliguria and the avarage duration was 4.8±8.7 (2-27) days. The avarage of the staying period in the hospital was 11.7±7.6 ( 4-28 )days. Hemodialysis was applied to 17 cases (47%), and not needed for 19 cases (53%). Conclusion: ARF related to the pregnancy was seen commonly in the third or the later pregnancies and the most common reasons were HELLP Syndrome, placenta detachment, and postpartum hemorrhage and resulted in a high risk condition for fetal and maternal mortality therefore, we think that the number of the pregnancies should be limited and especially multipar pregnancies must be closely controlled for ARF.

Highlights

  • In the developed countries decrease in acute renal failure (ARF) incidence occured because of the legality of the abortion and the developments in the antenatal care

  • In 24 of the ARF cases (67%) had hypertension at the time of the diagnosis whereas six cases (17%) had hypotension related to the vaginal bleeding

  • ARF related to the pregnancy was seen commonly in the third or the later pregnancies and the most common reasons were HELLP Syndrome, placenta detachment, and postpartum hemorrhage and resulted in a high risk condition for fetal and maternal mortality we think that the number of the pregnancies should be limited and especially multipar pregnancies must be closely controlled for ARF

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Summary

Introduction

In the developed countries decrease in ARF incidence occured because of the legality of the abortion and the developments in the antenatal care. There had been a difference between the developed and undeveloped countries about the frequency and the etiology of the ARF because of some environmental and socioeconomic reasons [1,2,3]. Before the years 1960-1970 all the ARF cases in women were related to the pregnancy and the ratio was 40-50%, and this was effecting the 1/ 2000-5000 of the all pregnancies. Today this ratio has decreased to 5% and 1/10000. This situation causes high risk for maternal mortality (9-55%) [4,5,6,7,8]

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