Etiological study of viral diarrhea among children under 5 years of age in Dongcheng district of Beijing

Abstract

Objective To investigate the main pathogens of viral diarrhea in children under 5 years old in Dongcheng District of Beijing. Methods From October 2011 to September 2015, 1 754 fecal specimens of children under 5 years old with diarrhea were collected in second maternal and child health care hospital of Dongcheng District. RT-PCR and PCR were used to detect Rotavirus (HRV), norovirus (NV), sapovirus (SAV), enteric Adenovirus (EAdV) and astrovirus (AstV). Results Among 1 754 specimens, 632 specimens were positive and the total detection rate was 36.0% (632/1 754). The detection rate of HRV, NV, SPV, EAdV and AstV were 12.4%, 10.1%, 5.4%, 9.4% and 3.5% respectively. The total positive rate is high from October to February of next year. The detection rate of EAdV was higher in 24~60 months of age, and the detection rates of others were higher in 6~24 months of age. There was no significant difference in the detection rates between male and female patients (x2=0.276, P>0.05). Conclusions Five kinds of viruses can be detected in infants with diarrhea. HRV and NV were the main pathogens. The detection rate of EAdV was significantly higher than other areas in China. Key words: Children under 5 years of age; Viral diarrhea; Etiology