Etiological structure and clinical manifestations of influenza in Khanty-Mansiysk autonomous District-Ugra

Abstract

The aim of the study was to examine the incidence of influenza in epidemic seasons from 2000 to 2017 in Khanty-Mansi Autonomous Okrug — Yugra, analysis of selected pathogens flu, clinical course, outcomes, risk and contingent. Used by the Russian Agency management database Khanty-Mansijsky autonomous region-Yugra weekly influenza morbidity, hospitalization, deaths, results of antigenic analysis of selected influenza viruses (1203 biosample) various age groups of the population from 22-x administrative territories district. Clinical-Laboratory conducted a survey of 133 hospitalized patients, of whom 70 patients over 18 years and 63 child aged 7 months to 9 years. Results: when analyzing the highest rates of flu were reported in the period 2000-2007, with a significant reduction in the beyond. The incidence of flu is caused by a prior distribution of influenza A (H1N1-pdm), seasonal influenza A (H1N1) and influenza A (H3N2). Epidemic season 2016/17, due to the simultaneous circulation of influenza A virus (N3N2) (52.1%), influenza A (H1N1) (39.6%) and influenza virus B (8.3%), was the longest. High proportion of flu registered among children under 6 years (79%), as well as in non-immunized population (95%). Compared with adults, children with influenza A (H1N1-pdm) is characteristic fever lasting more than 3 febrile-x days (100%), a combination of intoxic index with qatar syndrome of the upper respiratory tract, 2 times more likely to develop viral and bacterial pneumonia (23.8%). See influenza antiviral therapy high efficiency drug oseltamivir (Tamiflu) in children and adults.