Abstract
The title compound, C23H19FN2O3S, a fused-pyrimidine derivative, displays dihedral angles between the thiazole ring and the benzene ring and substituted benzene ring of 7.10 (14) and 3.48 (12)°, respectively. The dihydropyrimidine ring adopts a flattened boat conformation. The olefinic double bond is in a Z configuration.
Highlights
The title compound, C23H19FN2O3S, a fused-pyrimidine derivative, displays dihedral angles between the thiazole ring and the benzene ring and substituted benzene ring of 7.10 (14) and 3.48 (12), respectively
The olefinic double bond is in a Z configuration
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: NG5248)
Summary
Key indicators: single-crystal X-ray study; T = 293 K; mean (C–C) = 0.004 A; R factor = 0.052; wR factor = 0.147; data-to-parameter ratio = 14.8. The title compound, C23H19FN2O3S, a fused-pyrimidine derivative, displays dihedral angles between the thiazole ring and the benzene ring and substituted benzene ring of 7.10 (14) and 3.48 (12), respectively. The dihydropyrimidine ring adopts a flattened boat conformation. The olefinic double bond is in a Z configuration. Related literature For related crystal structures, see: Hou (2009); Kulakov et al (2009). For background to the biological properties of fusedpyrimidine derivatives, see: Alam et al (2010); Al-Rashood & Abdel-Aziz (2010); Ashok et al (2007); Jang et al (2011); Wichmann et al (1999);. For background to the biological properties of fusedpyrimidine derivatives, see: Alam et al (2010); Al-Rashood & Abdel-Aziz (2010); Ashok et al (2007); Jang et al (2011); Wichmann et al (1999);. Zhou et al (2011)
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