Abstract

293 K, R = 0.084 for 2966 observed reflections. The methoxy groups are nearly coplanar with the phenyl ring [maximum deviation from plane 0.18 (18)A], and pairs of molecules are connected by N H . . . N hydrogen bonds across a centre of symmetry. I n t r o d u e t i o n . Derivatives of benzothiazinone have anti-inflammatory activity (Lombardino & Wiseman, 1971) and are known to affect the central nervous system (Sianesi, Redaelli, Magistretti & Massarani, 1973). Sulphonamides, similar in structure to benzothiazinone, have been synthesized (Camoutsis & Catsoulakos, 1976, 1980; Catsoulakos & Camoutsis, 1980) and are being tested for pharmacological properties. Crystallographic studies of a series of these compounds are being carried out (Hamodrakas & Filippakis, 1977; Hamodrakas, Filippakis & Sheldrick, 1977; Hamodrakas, Akrigg, Sheldrick & Camoutsis, 1978; Perdikatsis, Catsoulakos & Filippakis, 1979; Panagiotopoulos & Filippakis, 1980; Panagiotopoulos, Filippakis & Catsoulakos, 1980) in attempts to relate structure and activity. The title compound is a member

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