Abstract
In the title compound, C24H26N4O3, the pyrazolo[1,5-a]pyridine ring system makes dihedral angles of 38.130 (3) and 30.120 (3)°, respectively, with the isoxazole and phenyl rings. In the crystal, two molecules are linked by a pair of C—H⋯N hydrogen bonds, forming a centrosymmetric dimer. A weak intramolecular C—H⋯O interaction is also present.
Highlights
In the title compound, C24H26N4O3, the pyrazolo[1,5-a]pyridine ring system makes dihedral angles of 38.130 (3) and 30.120 (3), respectively, with the isoxazole and phenyl rings
Two molecules are linked by a pair of C—HÁ Á ÁN hydrogen bonds, forming a centrosymmetric dimer
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: IS2515)
Summary
Key indicators: single-crystal X-ray study; T = 298 K; mean (C–C) = 0.004 A; R factor = 0.061; wR factor = 0.187; data-to-parameter ratio = 13.5. C24H26N4O3, the pyrazolo[1,5-a]pyridine ring system makes dihedral angles of 38.130 (3) and 30.120 (3), respectively, with the isoxazole and phenyl rings. Two molecules are linked by a pair of C—HÁ Á ÁN hydrogen bonds, forming a centrosymmetric dimer. A weak intramolecular C—HÁ Á ÁO interaction is present. Related literature For the bioactivity of pyrazolo[1,5-a]pyridine and isoxazole derivatives, see: Cuny et al (2008); Ge et al (2009); Johns et al (2005); Lanig et al (2001); Lee et al (2009). For the synthesis of ethyl 3-(5-((methylsulfonyloxy)methyl)isoxazol-3-yl)-2phenyl-H-pyrazolo[1,5-a]pyridine-5-carboxylate, see: Meng et al (2010)
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