Abstract
The asymmetric unit of the title compound, C24H27N3O4, contains two molecules, A and B. The benzimidazole rings are essentially planar [maximum deviations = 0.0144 (10) and 0.0311 (8) Å in A and B, respectively]. The dihedral angle between the benzimidazole mean plane and its attached benzene ring is 36.90 (5) ° for molecule A and 51.40 (5) ° for molecule B. In both molecules, the pyrrolidine ring adopts an envelope conformation with a C atom as the flap. In molecule B, the flap C atom is disordered over two positions in a 0.711 (6):0.289 (6) ratio. In the crystal, C—H⋯O interactions link the molecules, generating [100] chains. The crystal packing also features weak π–π interactions between the imidazole and benzene rings [centroid–centroid distances = 3.8007 (7) and 3.8086 (7) Å] and between the benzene rings [centroid–centroid distance = 3.7001 (7) Å] and C—H⋯π interactions involving the benzene rings.
Highlights
The asymmetric unit of the title compound, C24H27N3O4, contains two molecules, A and B
The benzimidazole nucleus is an important pharmacophore in drug discovery (Spasov et al, 1999)
The crystal packing are further stabilized by weak C—H···π interactions (Table 1) involving benzimidazole and benzene rings
Summary
The dihedral angle between the benzimidazole mean plane and its attached benzene ring is 36.90 (5) for molecule A and 51.40 (5) for molecule B. In both molecules, the pyrrolidine ring adopts an envelope conformation with a C atom as the flap. C—H O interactions link the molecules, generating [100] chains. The crystal packing features weak – interactions between the imidazole and benzene rings [centroid–centroid distances =. 3.8007 (7) and 3.8086 (7) Å] and between the benzene rings [centroid–centroid distance = 3.7001 (7) Å] and C—H interactions involving the benzene rings
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Acta Crystallographica Section E Structure Reports Online
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
