Abstract
In recent years, nanotechnology has a new era of drug delivery for many drug systems. Transdermal drug delivery is one of the few systems that have recently become a major focal point of research. When compared to traditional drug delivery systems, the Transdermal Drug Delivery System (TDDS) has various advantages. Due to the barrier properties of the Stratum Corneum, TDDS has had limited market success. The introduction of ethosomes, which are soft, malleable vesicular carriers containing ethanol and are tailored for enhanced delivery of active agents, has opened up a new area of vesicular research for transdermal drug delivery. According to various reports, ethosomes have a promising future in improving the efficacy of transdermal delivery of various agents. Ethosomes are also useful for the non-invasive delivery of small, medium and large drug molecules. Ethosome preparation is simple, requires no complicated equipment, and can thus be scaled up to industrial levels. The review emphasises introduction to ethosomes, their composition and preparation methods, evaluation, and their efficiency in penetrating the skin and the use of ethosomes in transdermal medication delivery as being more effective than liposomes or hydroalcoholic solution in terms of quantity and depth.
 Keywords: Ethosomes, Novel carriers, Transdermal Drug Delivery System
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