Ethopharmacology: A historical perspective

Abstract

Ethopharmacology can be defined as the study of behavioral and other effects of drugs through the use of ethological concepts. The study of drug effects on natural action patterns (motor acts and postures listed in ethograms), with respect to natural settings and to behavior as a whole (all identifiable behaviors occurring during the measurement) represents the basic concepts of ethopharmacology. Although pioneers drew attention to the potential of the ethological approach in pharmacology in the early 1960s, the number of publications utilizing this approach has steadily grown only since the mid-1970s. In the 1980s, modern technology, such as videorecorders, microcomputers and software, has been more widely applied in ethopharmacological experiments, greatly facilitating the observation and quantitative analysis of multiple data. Ethopharmacology is not "another" behavioral pharmacology, but an integral part of it. Rather, it represents one of the tools which can be useful (and sometimes even indispensable) in achieving a better understanding of the behavioral effects of drugs. It is to be hoped that it will be used in concert with other approaches in the future.