Abstract
Bridelia micrantha is traditionally used in tropical Africa to treat a wide range of human and animal diseases. The aim of this study was to summarise the research that has been done on the ethnomedicinal uses, phytochemistry and pharmacological properties of B. micrantha so as to understand its importance and potential value in primary healthcare systems. The literature search for information on ethnomedicinal uses and pharmacological activities of B. micrantha was undertaken using databases such as Web of Science, Scopus, Google Scholar, Science Direct, BioMed Central (BMC), PubMed and Springerlink. Other relevant literature sources included books, book chapters, websites, theses, conference papers and other scientific publications. This study showed that B. micrantha is used as herbal medicine in just over half (57.3%) of the countries in tropical Africa where it is indigenous. A total of 54 ethnomedicinal uses of B. micrantha have been recorded with a high degree of consensus on burns, wounds, conjunctivitis, painful eyes, constipation, gastric ulcers, cough, headache, rheumatism, painful joints, dysentery, ethnoveterinary medicine, malaria, sexually transmitted infections, stomach ache, tape worms and diarrhoea. Different plant parts, aqueous and organic extracts exhibited anthelmintic, antimicrobial, anticonvulsant and sedative, antidiabetic, antidiarrhoeal, antinociceptive, antioxidant, antiplasmodial, antischistosomal, hepatoprotective, insecticidal and β-lactamase inhibitory activities.
Highlights
IntroductionBridelia micrantha (Hochst.) Baill. is a small to medium sized tree belonging to the family
Bridelia micrantha (Hochst.) Baill. is a small to medium sized tree belonging to the familyPhyllanthaceae, commonly known as mitzeerie or coastal golden leaf [1].The genus name “Bridelia” was coined in honour of Samuel Elisée Bridel-Brideri (1761–1828), a Swiss-German muscologist [2]
B. micrantha extracts are characterized by weak antiplasmodial activities [59,90,91], these results provide compelling evidence for the rationale of the species as malaria remedy in Guinea [57], Ivory Coast [58], Kenya [56] and Tanzania [20,59]
Summary
Bridelia micrantha (Hochst.) Baill. is a small to medium sized tree belonging to the family. The genus Bridelia includes approximately 60–70 species found throughout tropical and subtropical regions of the world, Africa and Asia [3,4]. Due medicinal to its popularity tree in Tanzania as a herbal [9]. B. micrantha is an important timber tree species in tropical Africa, and the handles in Ethiopia [1,14]. The present review isthe aimed atthe documenting the the validation of the ethnopharmacological uses of the species. Results of thi al activities and the uses, correlated biological chemical activities compounds and the correlated of micrantha chemical with compounds emphasis on of micrantha with emphasis on ethnomedicinal uses, biological activities and the correlated chemical compounds of B. micrantha with research challenges andofperspectives to address the knowledg of the ethnopharmacological the validation ofvalidation of thethe ethnopharmacological species.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
