Abstract
Drugs of traditional system of medicine including Unani and Ayurveda are recommended and used in various diseases since long. These drugs are mainly derived from herbs and plants. Neem is a pre-eminent and a sacred gift of nature. This tree is still regarded as “Wonder tree”, “Nature’s drug store”, “Divine tree”, “Heal all”, “Materia medica”, “Panacea of all diseases” and “Village dispensary” also considered as “An ancient cure for modern world”. In Unani System of Medicine (USM) it is widely used as antiinfective agent in various skin diseases (Amrāḍ-i Jild) such as leprosy, syphilis, tinea, itching and in ulcers. It is very effective in painful menses and dysmenorrhea, chronic joint pain, constipation, intestinal warm (Kirm-i Shikam) and also prefer in the killing of head lices, diabetes and rheumatic arthritis. This study is based on a comprehensive analysis of related articles published in journals using the phrases "Neem or Azadirachta indica ", "Neem research paper", "Neem and Unani Medicine" and "Neem used in traditional medicine" in electronic searches of the PubMed, SCOPUS, Google Scholar advanced search and AYUSH Research Portal. The evidence based scientific and clinical studies reported in the present review confirming the therapeutic efficacy of Azadirachta indica (Neem). Biological active phytoconstituents of Neem also indicate that it may serve as very effective natural medicine in different disease. In this aspect, further in vitro and in vivo studies are needed in respect to explore the recommendations of USM as well as other traditional system of medicines in term of the extensive therapeutic values of Azadirachta indica.
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