ETHNOBOTANICAL USES, PHYTOCHEMISTRY AND PHARMACOLOGICAL ACTIVITIES OF PEPEROMIA PELLUCIDA (L.) KUNTH (PIPERACEAE)-A REVIEW

Raghavendra H L,Prashith Kekuda T R

doi:10.22159/ijpps.2018v10i2.23417

Raghavendra H L, Prashith Kekuda T R

Open Access

https://doi.org/10.22159/ijpps.2018v10i2.23417

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Abstract

Peperomia pellucida (L.) Kunth is a herb belonging to the family Piperaceae. In this review, an extensive literature survey was carried out to compile information available on medicinal uses, phytochemistry and pharmacological properties of P. pellucida. The plant is used as food, flavoring agent and as medicine. The plant is used as medicine for treating various ailments or disorders such as asthma, rheumatism, wound, fever, stomach problems, kidney infection, hemorrhoid pain, joint pain, hypertension, diarrhea, snake bite and measles. The plant contains phytochemical groups such as alkaloids, flavonoids, saponins, terpenoids, steroids and glycosides. Compounds such as dill apiole, phytol, stigmasterol, sitosterol, secolignans, tetrahydrofuran lignans, highly methoxylated dihydronaphthalenone, peperomins, sesamin and isoswertisin have been identified in the plant. Studies have shown that the plant exhibited several pharmacological activities such as antimicrobial, antioxidant, anti-angiogenic, anti-inflammatory, analgesic, antipyretic, neuropharmacological, antisickling, anticancer, enzyme inhibitory, antiulcer, hypotensive, immunostimulatory, fracture healing and antidiabetic activities which support the traditional use of the plant. Purified chemicals from the plant have also shown to exhibit certain pharmacological activities such as antiulcer, anticancer and antimicrobial activity. By this extensive literature review, it can be concluded that P. pellucida can be utilized as a promising candidate for developing newer drugs with potent pharmacological activities.

Highlights

Throughout the world, especially developing and under-developing countries, plants have been exploited as medicine to meet primary healthcare needs
We presented updated information concerned with the ethnobotanical uses, phytochemical composition and pharmacological properties of P. pellucida
A compound by name 3’,4’, dihydroxy-3-5-dimethoxy flavone-7-O-β-rhamnose was isolated from ethyl acetate fraction of crude methanolic extract of aerial parts of P. pellucida and the structure was elucidated by the spectral data [43]

Summary

Introduction

Throughout the world, especially developing and under-developing countries, plants have been exploited as medicine to meet primary healthcare needs. A compound by name 3’,4’, dihydroxy-3-5-dimethoxy flavone-7-O-β-rhamnose was isolated from ethyl acetate fraction of crude methanolic extract of aerial parts of P. pellucida and the structure was elucidated by the spectral data [43]. Nwokocha et al [70] evaluated hypotensive activity of aqueous extract from whole plant of P. pellucida in rat model.

Results

Conclusion