Abstract
Overweight and obesity are pathologies that increase dramatically, they are most often associated with diseases such as hypertension, heart failure, stroke, type II diabetes, insulin resistance, dyslipidemias, certain cancers etc .The objective was to conduct an ethnobotanical survey of 4 plants consumed during periods of hunger and to determine the effect of the extracts of these plants on weight gain and food intake.The survey was based on direct dialogue using the respondent's choice language and the use of a questionnaire. Acute toxicity was determined on NMRI mice by orally administering of single dose of 2000 mg/kg. The slimming and anorectic potential of plant extracts was to evaluate the effect of plant extracts on weight gain and food intake of animals treated at 50, 100 and 500 mg/kg. 55 person with an age between 40 and 81 years old were interviewed. Raphionacme daronii gave the highest frequency of citation with 25.42%. All plant species showed no toxicity at 2000 mg/kg. Gardenia erubescens at 50 mg/kg gave a good activity on weight gain with a reduction of 5.18% against the control with an increase of 11.02%. Gardenia erubescens at 500 mg/kg gave the best anorectic activity on the treated animals.These plant extracts are an asset in the search for a new natural and less toxic molecule for the fight against obesity.
Highlights
Obesity, called a global epidemic by the World Health Organization (WHO), has multiple harmful effects as well on the sanitary level as economic and human
The survey was conducted on four (4) species of plants frequently used during periods of famine, namely, Raphionacme daronii, Gardenia erubescens, Leptadenia hastata, Balanites aegyptiaca
Ethnobotanical survey During the survey we interviewed 55 people between the ages of 40 and 81 years old; more than 50% of whom are between 50 and 70 years old
Summary
Obesity, called a global epidemic by the World Health Organization (WHO), has multiple harmful effects as well on the sanitary level as economic and human. Burkina Faso, like Sahelian countries, has often been confronted in times of famine [4] During these periods of food shortage, people usually resort to plants that have appetite suppressant effects. Taking a supplement of these appetite suppressants may help you lose weight by reducing appetite and cravings The activity of these plant species is certainly related to the presence of metabolites such as glycosilated pregnanes [5], mannans [6], caffeine [7,8], mucilage, phenylalanine [9,10], which can cause anorexia, reduce triglycerides or inhibit the enzymes involved in lipid metabolism such as pancreatic lipase, lipoprotein lipase and glycerophosphate dehydrogenase or to increase energy expenditure. All these mechanisms result in a reduction of fat mass and body weight
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
