Abstract
The Department of Health and Human Services Framework for Guiding Funding Decisions about Proposed Research Involving Enhanced Potential Pandemic Pathogens (PPPs) contains a series of principles for governing the funding and conduct of gain-of-function (GOF) research resulting in the creation of PPPs. In this article, I address one of these principles, governing the replacement of GOF research with alternate experiments. I argue that the principle fails to address the way that different experiments can promote the same values as those promoted by GOF research resulting in PPPs. I then address some objections to this claim, and provide policy recommendations moving forward.
Highlights
Specialty section: This article was submitted to ELSI in Science and Genetics, a section of the journal Frontiers in Bioengineering and Biotechnology
Decisions about Proposed Research Involving Enhanced Potential Pandemic Pathogens (PPPs) contains a series of principles for governing the funding and conduct of gain-offunction (GOF) research resulting in the creation of PPPs
I argue that the principle fails to address the way that different experiments can promote the same values as those promoted by GOF research resulting in PPPs
Summary
Specialty section: This article was submitted to ELSI in Science and Genetics, a section of the journal Frontiers in Bioengineering and Biotechnology
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