Abstract
Ethical and methodological considerations on conducting clinical research in poor and low-income countries: Viewpoint of the authors of the BEST TRIP ICP randomized trial in Latin America.
Highlights
Title Ethical and methodological considerations on conducting clinical research in poor and lowincome countries: Viewpoint of the authors of the BEST TRIP intracranial pressure (ICP) randomized trial in Latin America
As stated in the BEST TRIP report, this was not a study of intracranial pressure (ICP) monitoring was designed as an investigation of two protocols of aggressive treatment of intracranial hypertension, on driven by monitored ICP and based on recommendations from the Guidelines for the Management of Acute Brain Injury in Adults[1] and the other based on current practices at the study institutions, which were guided by serial neurological examination and CT imaging
From a position of academics in high-income countries (HICs), it is argued that ICP monitoring is the standard of care
Summary
Title Ethical and methodological considerations on conducting clinical research in poor and lowincome countries: Viewpoint of the authors of the BEST TRIP ICP randomized trial in Latin America. Ethical and methodological considerations on conducting clinical research in poor and low-income countries: Viewpoint of the authors of the BEST TRIP ICP
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