Abstract
Vitamin C deficiency, although reducing microsomal aniline hydroxylase and NADPH oxidase activities and decreasing the amount of cytochrome P-450, had no effect on the rate in vivo of ethanol elimination. Ethanol given as a daily oral dose of 2.5g/kg for 14 days did not induce microsomal enzyme activities or increase the concentration of microsomal electron transport components. Drugs that are metabolized by the microsomal drug metabolizing system have increased plasma half lifes in scorbutic guinea-pigs, but no decrease in ethanol disappearance from the blood in the scorbutic animals used in the present study was noted. It is concluded that when ADH activity is normal, no further systems are required for ethanol metabolism.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
