Abstract

We are honored by the interest of Iseman and Fennely in our case, and we respect their vast knowledge and experience with acid-fast bacilli (AFB) and granulomatous inflammation. Teasing through the differential diagnosis for granulomatous lung inflammation can be challenging. Conclusions often are fraught with controversy,1 particularly when microorganisms are not identified in tissue stains. Temporal relationships in the clinical history help to define the likelihood of an applicable diagnosis.

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