Estudio de función sistólica cardiaca en pacientes desnutridas por anorexia nerviosa y correlación con parámetros nutricionales

Abstract

Introduction/ObjectivesThere are discrepancies in the data on the presence of systolic dysfunction, measured using the left ventricular ejection fraction (LVEF) in patients with anorexia nervosa. The aim of this study is to measure left ventricular systolic function using Tissue Doppler and Speckle-tracking and see if there is any correlation with nutritional parameters. MethodsA transthoracic echocardiogram was performed on 16 anorexic patients with a Body Mass Index (BMI)<18.5. The LVEF was measured using Simpson's method, and the mitral annulus systolic velocity (SV) and Longitudinal Strain (LS) by Tissue-Doppler. Several nutritional parameters were also determined in plasma. A descriptive analysis and bivariate correlations (Spearman correlation coefficient) were performed. ResultsThe mean BMI of the sample was 17.38±0.12kg/m2, and mean weight 44.68±9.46kg. The systolic function parameters were, LVEF 59.06±5.64%, LV SV 0.0787±0.015m/s, and LS −20.72±2.47%. A strong and statistically significant correlation was found between the LS and a low plasma magnesium (−0.819, P<.01), with a weaker one between LS and VitaminB12 (−0.614, P=.044). ConclusionsOur data appears to go against a possible systolic dysfunction in patients with malnourishment due to anorexia nervosa. The strong inverse association between the LS and plasma levels of magnesium and VitaminB12 is highlighted.