Abstract
Summary The gastric secretory response in patients and monkeys was studied before, during, and after treatment with estrogens. No significant decrease in acid or pepsin secretion could be demonstrated, although a suggestion of a decrease in acid secretion was noted. This does not, by itself, explain the alleged benefits of estrogens on the course of peptic disease and neither does it explain some of the well recognized sex differences in peptic disease and acid secretion.
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