ESTROGENIC EFFECTS UPON TUBAL CONTRACTILITY AND THE VAGINAL SECRETION IN THE MENOPAUSE STUDY OF 24 CASES WITH THE AID OF UTEROTUBAL INSUFFLATION1

Abstract

IN A PAPER read before the American Gynecological Society, May 1932, Rubin (1) reported his experience with insufflation in 7 women of the menopause age. There were no tubal contractions in 3 instances, while in 4 of the 7 cases the contractions were infrequent and barely reached an amplitude over 5 mm. Hg. He also considered the possible influence of ovarian hormonal function on the fallopian tubes in relation to the different phases of the ovarian cycle. From comparative observations of many graphs obtained during clinical tubal insufflation, a definite impression was gained that there was a possible relationship between tubal contractions and the ovulation menstruation cycle. This impression gained from clinical experience with the test for tubal patency led Rubin (2, 3) to suggest in 1927 and in 1928 that parallel investigations be “carried out in estimating the quantity of female sex hormone.” Along the same line of investigation, Morse and Rubin (4) applied the method of uterotubal insufflation in t...