Abstract
Objective To investigate the curative effect of estrogen therapy on urinary tract infection of type 2 diabetes mellitus in postmenopausal women. Methods Eithty-three postmenopausal women who had urinary tract infection of type 2 diabetes mellitus were enrolled and were randomly divided to receive antibiotic therapy(levofloxacin was used before obtaining of drug susceptibility results) alone (control group) or in combination with estradiol gel (treatment group). The clinical efficacy and bacteriological therapeutic effect in the two groups were evaluated. Results The treatment group was better than control group in both clinical efficacy and bacteriaological therapeutic effect. Conclusions Antibiotic therapy in combination with estradiol gel showed remarkable efficacy for patients with type 2 diabetes mellitus associated with urinary tract infection in postmenopusal women. Key words: Type 2 diabetes mellitus; Urinary tract infection; Estrogen; Postmenopausal
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