Abstract

I. IntroductionII. The Concept of Local Estrogen BiosynthesisIII. Aromatase and Its GeneIV. The ArKO MouseV. The ArKO Mouse and the Metabolic SyndromeVI. The Metabolic Syndrome in Humans with Natural Mu-tations in AromataseVII. Summary of the Metabolic Effects of EstrogensVIII. Local Aromatase Expression in the Breast and BreastCancerIX. Role of LRH-1 in Aromatase Expression in the Breast

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