Abstract
This study examined the effects of unopposed estrogen replacement therapy (ERT) on the cognition and clinical course of women who have been diagnosed with probable Alzheimer’s disease. The records of 99 women diagnosed with probable Alzheimer’s disease according to NINCDS-ADRDA criteria, and in some cases autopsy confirmed as well, were analyzed. Depression, education, and age were all considered in the analysis. Results suggest that after an average of four years after symptoms appeared, women on ERT at the time of their diagnoses had similar cognitive functioning compared to those who are not on ERT. There were, however, significant differences in the clinical course of the illness between the two groups, with the non-ERT group reporting more “non-memory” problems as initial symptoms in addition to a having greater degree of overall behavioral deficit in activities of daily living.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
