Estrogen receptor, a marker for human breast cancer differentiation and patient prognosis.

Abstract

Breast cancer is the leading cause of cancer death in American women. Over the past 80 years this malignancy has been studied intensively not only because of its high incidence, but also because of interest generated by the original observation of Beatson demonstrating that some tumors are hormone dependent. Unfortunately, it has only been over the past decade that real advances have been made in the treatment of this disease, as well as in our understanding of breast tumor biology and natural history.KeywordsBreast CancerEstrogen ReceptorPrimary Breast CancerNuclear GradeEstrogen Receptor StatusThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.