Abstract
Analytical results represent a very important part in a quality control program. Uncertainty estimation is an important step in method validation. The objective of this paper is to study the uncertainty of measurement estimation in the quantitative determination of codeine phosphate from pharmaceutical formulations using UV-VIS spectrophotometry. The uncertainty estimation was performed using the Ishikawa diagram. The estimation of uncertainty components proved to be a good way for the experimental model to obtain low contribution of uncertainty to the analytical result.
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