Abstract

The function of a total body counter for many clinical uses can be specified in terms of the largest acceptable standard error of the retention estimate. A method of evaluating these standard errors is described which can also be used quite generally in radioisotope studies. The standard error of retention is used here to investigate the relative importance of the background count, the counter efficiency and the quantity of radioactive material administered to the patient. It is shown that two sodium iodide crystals 10 cm in diameter with simple shielding arrangements are quite adequate for a number of clinical absorption studies.

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