Abstract
The surface layer of the urban atmosphere significantly affects human health. Its quality depends on the level of air pollution. The aim was to determine the size distribution of suspended particulate matters (SPMs) in the atmospheric surface layer of Vladivostok city and to assess the response of the blood immune and metabolic parameters of the population with bronchopulmonary pathology. Sampling of SPMs was conducted in the continental zone of the city with a high level of technogenic pollution (138 samples) and the island part of the city with an insignificant level of technogenic pollution (132 samples). The SPM fractional composition was analyzed by laser granulometry. We examined patients with bronchopulmonary pathology living in a one-kilometer zone centered on sampling area for at least 5 years (continental territory—220 patients, island territory—176 patients). We calculated the D% index characterizing the integral response of the blood immune and metabolic parameters to the exposure of dust fractions. It was found that PM > 10 (mainly of a natural origin) predominate in the island zone with insignificant level of technogenic pollution. The PM10 fraction prevails in the area with a high level of technogenic pollution. The response of the immune and metabolic systems to the exposure to microparticles in population living in the marine and forest/park zone of the island indicates a health-improving effect of the area. Low values of D% were detected for the patients living in the area with a high air pollution level, indicating a pathogenic reaction of immune and prooxidant-oxidative systems.
Highlights
IntroductionOxidative stres systemic inflammatory response play an important role in the pathogenesis of chopulmonary diseases [16]
The analysis showed that 10–50 μm suspended particulate matters (SPMs) predominated in the island part of the city
In Vladivostok city, it was found that PMs >10 of natural origin prevail in the atmospheric surface layer in the green coastal zone with insignificant technogenic pollution
Summary
Oxidative stres systemic inflammatory response play an important role in the pathogenesis of chopulmonary diseases [16] These two processes are mutually influential and als resent the key targets of exposure to fine and ultrafine dispersed air toxicants, entails negative consequences for the respiratory system and the whole organism response of the blood immune and metabolic parameters is a diagnostic and prog in the pathogenesis of bronchopulmonary diseases [16]. These two processes are mutually criterion and for the status oftargets the population an urbanized influential health represent the key of exposure in to fine and ultrafinearea
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