Abstract

Estimation of the prostate volume with ultrasound offers many advantages such as portability, low cost, harmlessness, and suitability for real-time operation. Abdominal Ultrasound (AUS) is a practical procedure that deserves more attention in automated prostate-volume-estimation studies. As the experts usually consider automatic end-to-end volume-estimation procedures as non-transparent and uninterpretable systems, we proposed an expert-in-the-loop automatic system that follows the classical prostate-volume-estimation procedures. Our system directly estimates the diameter parameters of the standard ellipsoid formula to produce the prostate volume. To obtain the diameters, our system detects four diameter endpoints from the transverse and two diameter endpoints from the sagittal AUS images as defined by the classical procedure. These endpoints are estimated using a new image-patch voting method to address characteristic problems of AUS images. We formed a novel prostate AUS data set from 305 patients with both transverse and sagittal planes. The data set includes MRI images for 75 of these patients. At least one expert manually marked all the data. Extensive experiments performed on this data set showed that the proposed system results ranged among experts’ volume estimations, and our system can be used in clinical practice.

Highlights

  • Estimation of the prostate volume with ultrasound offers many advantages such as portability, low cost, harmlessness, and suitability for real-time operation

  • Clinicians use prostate volume while managing lower urinary tract symptoms (LUTS) [3]. Another critical area for prostate volume is the calculation of the Prostate-Specific Antigen Density (PSAD) value to detect and manage prostate cancer (PCa) [4]

  • This study aimed to demonstrate that an Abdominal Ultrasound (AUS)-based automated system for measuring the prostate volume can be an alternative to TRUS, Magnetic Resonance Imaging (MRI), or Computed Tomography (CT)-based systems

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Summary

Introduction

Estimation of the prostate volume with ultrasound offers many advantages such as portability, low cost, harmlessness, and suitability for real-time operation. Our system detects four diameter endpoints from the transverse and two diameter endpoints from the sagittal AUS images as defined by the classical procedure. These endpoints are estimated using a new image-patch voting method to address characteristic problems of AUS images. Extensive experiments performed on this data set showed that the proposed system results ranged among experts’ volume estimations, and our system can be used in clinical practice. Prostate volume is a crucial parameter in many clinical practices It plays an essential role in the diagnosis of benign prostatic hyperplasia (BPH) [1].

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