Estimation of the physiochemical characteristics of an antibiotic drug using M-polynomial indices

Abstract

Antibiotics are more effective against intracellular bacterial infections. However, with continuous administration of antibiotics, cells acquire drug resistance. The bioconjugated Geranyl and farnesyl penicillin G is the best antibiotic to reduce the replication of bacteria inside the cells as compared to untreated cells. Topological index is a technique used for understanding the fundamental topology of chemical compounds investigated by the quantitative structure-properties relationship (QSPR). Özge Çolakoğlu Havare [43] developed the QSPR relation between M-polynomial indices and physiochemical characteristics. In this article, we have calculated the degree-based M-polynomial indices for the geranyl and farnesyl penicillin G bioconjugate structure. Based on the results of Özge Çolakoğlu Havare article, we can say that our computed results for antibiotic drug are helpful for predicting the physiochemical characteristics.