Abstract
A study was made of the potentiometric titration of a number of official salts of weak organic acids, notably sodium benzoate, sodium acetate, sodium propionate, barbital sodium, phenobarbital sodium, sulfathiazole sodium and sulfadiazine sodium, using a solvent mixture of propylene glycol and isopropyl alcohol and perchloric acid in the same solvent as a titrant. The results were compared with results obtained by the empirical use of indicators. In some instances when the potentiometric end point, determined with a Fisher titrimeter, gave low results, the empirical use of methyl orange or methyl red gave satisfactory results.
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More From: Journal of Pharmaceutical Sciences (Scientific Edition)
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