Estimation of second-, third- and fourth-order nonlinearity parameters for specific fluorocarbon drug-delivering nanosystems

Abstract

The nonlinear B/A, C/A and D/A are new parameters in ultrasound fluorocarbon nanosystem characterisation. In this article, all the three parameters are estimated for specific fluorocarbons, such as perfluorohexane (C6F14), perfluoroheptanes (C7F16), perfluoro-1-butyl tetrahydrofuran (C8F16O), perfluoro octanes (C8F18), perfluorodecalin (C10F18), perfluorodichloro octane (C8F16Cl2) and perfluorooctyl bromide (C8F17Br) through their experimental ultrasonic velocity for different temperatures. The fluorocarbons under study are powerful drug-delivering agents. Since these parameters have not been so far calculated for such systems, it becomes more important to evaluate them. The range of all the three parameters of our results is highly encouraging. The values resemble the most of biological systems. It is interesting to note that the classical model also suits very well in nanoscales too.