Estimation of laser light propagation in biological tissue during laser-tissue bonding using Monte Carlo simulation

Abstract

Monte Carlo simulations are an elementary approach towards modeling light propagation in tissues. The detection of subsurface temperature in tissues during laser mediated therapies and microsurgeries is crucial for estimating associated thermal damage. MC simulation provides with the possibility to optimize the process. The approach has been used to model light propagation, associated energy deposition, and the temperature distribution inside the tissue. Understanding the extent of laser light transmittance and heat distribution within the tissue is crucial for minimizing damage to the adjacent biological tissues. The total photon weight absorbed estimates the total heat distribution within the volume. A three-layer heterogeneous tissue was specified consisting of only the epidermis, dermis, and the subcutaneous fat tissue. The hop, drop, and spin trail of photons depends on the optical properties of these layers. The energy deposition and temperature distribution estimation are obtained by the MC simulation method. A real-time measurement of the temperature profile was also performed. The experimental results were in close congruence with the simulation result. The simulation results show good reproducibility of the real temperature distribution. Monte Carlo method can, thereby, be used in estimation and optimization laser induced processes.