Abstract

The activity of fungitoxic agents was evaluated by testing on the basis of change in growth rate of fungal mycelium in the presence of such compounds. Instead of the heretofore chemical compounds as used standards for determining the degree of inhibition, the results are based on an estimation of biological activity (measured as the rate of growth of the mycelium) of the microorganism and the factor of growth activity is introduced. For the estimation itself it is suggested to assess the mycelium-static activity of the compounds tested. In estimating the fungistatic effect of some compounds on the mycelium and on the conidiospores of lower fungi it was found that fungal mycelium is more resistant toward toxic agents (benzoic acid, methyl р-hydroxybenzoate, sodium pentachlorphenate, derivatives of methoxyphenoxyacetic acid and dehydroacetic acid) than are conidiospores.

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