Estimation of D-Dimer Level among Sudanese Patients with COVID-19 Infection-Khartoum State 2022

Abstract

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirusdisease 2019 (COVID-19) has rapidly evolved from an epidemic outbreak in Wuhan, China into a pandemic infecting more than one million individuals all over the world, where as billions of citizens are affected by measures of social distancing and the socioeconomic impact of the pandemic
 Material and methods: This was case control study, conduct at COVID-19 quarantine hospitals in Khartoum state during the period from May to July 2022, for the measurement of D-dimer level among Sudanese covid 19 patients. One hundred participants were selected as cases and apparently fifty participants were selected as control group. 2.8 ml of venous blood samples were collected in Tri Sodium Citrate anticoagulant The D-dimer was performed using B50protein analyzer .
 Results: When compared the D-dimer results between case and control there was highly significant difference with p.value 0.000. In addition the D-dimer in cases compared with the other study variables which revealed; significant differences with the chronic disease and the severity of the disease, in significant differences with the age, gender and smoking status.
 Conclusion: This study concluded that D-dimer was significantly increase in COVID-19 patients, and it had significant differences with the chronic disease and the severity of the disease, insignificant differences with the age, gender and smoking status.
 Keywords: COVID-19, SARS-CoV-2, D-dimer, chronic disease and B50protein analyzer