Abstract
THE need for some diagnostic test to differentiate infection of the upper from that of the lower urinary tract is well recognized. Prockop and Davidson1 suggested that, since the kidney contains more lysozyme activity than any other tissue in the body, by measuring the increase in this activity it might be possible to pick out patients with renal disease. More recently Bank and Bailine2 reported that the activity of beta-glucuronidase, an enzyme concentrated in kidney lysosomes,3 was increased in the urine of patients with acute or chronic pyelonephritis as compared with those who had infections of the lower urinary tract. . . .
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