Estimation levels of Immunoglobulin and Complement in Amoebiasis patients (Amebic Dysentery)

Abstract

Background: Amebic dysentery is an infections causing by parasitic protozoan as Entamoeba histolytica which caused light to severe intestinal damage and in sometimes its spreading to the lungs, liver, brain and others organs, so it can be causing by closely related species of Entamoeba hartmanni and Entamoeba coli are commensals. Patients and methods: The samples was collected from patient reviewers to teaching Hospital/Baghdad city and ask them about information as age, sex, educational level, Residency and Income level, During (February–May) 2018, and Stool specimens and blood (5ml) from patients suffering from diarrhea then examined all specimens within thirty min. by General stool examination (Macroscopic and Microscopic examination and determined the concentration of immunoglobulin and complement (C3 & C4) by using Single Radial Immunodiffusion (SRID). Results of current study were found higher percentage of patients in the age group (1) as 45% , whilst decreased in age groups (2) to 23% , also results showed highly percentage in male (53.4) than female (46.6)%, also percentage of infection with Entamoeba histolytica was highest in Secondary as (36.6)% and followed by Non – study (illiterate people) as ( 34.4)%, so in urban ( 74.8) % more than rural (25.2)% as well as low Income level ( 53.5%) more than both good and high income level, also this study explain all concentrations of immunoglobulin and Complement were found high significant (p<0.001) in patients group than control group, Conclusion The infection with E. histolytica were highest in young old with age range from (1-15) years who live in rural areas, and high rate concentration of IgM ; IgG and IgE. Conclusions current study, infection with E. histolytica were highest in young old with age range from (1-15) years who live in rural areas, also high rate concentration of IgG, IgM and IgE in sera of amoebiasis patients than control group as well as the complement levels (C3&C4).