Abstract
PurposeThe purpose of this study is to come up with new methods to quantitate the blood loss under endoscope and explore the influence of blood loss on percutaneous endoscopic lumbar discectomy (PELD).MethodsClinical research and in vitro experiment are combined. In the in vitro experiment, 2.0-ml blood was diluted in different ratio to simulate the rinse solution of PELD, the hematocrit method (HCT-M) and red blood cell count method (RBC-M) were came up to estimate blood loss and the new methods were calibrated with the direct measurement method (Direct-M). In clinical research, 74 patients with L5/S1 disk herniation were treated with PELD, and HCT-M and the empirical method (EMP-M) were used to estimate the blood loss under endoscope. According to blood loss, all patients were divided into group A (≤ 10 ml) and group B (> 10 ml). The blood loss, operation time, fluoroscopy frequency, visual analog scale (VAS), and Oswestry Disability Index (ODI) scores were compared between the two groups.ResultsIn the in vitro experiment, the hematocrit of the rinse solution was always stable over time. The estimated blood loss by HCT-M was stable and quite approximate to actual blood volume (2.0 ml) whatever the blood dilution ratio, while according to RBC-M, the estimated blood loss was close to the actual blood volume only when the dilution ratio was greater than 300 times. In clinical research, the blood loss estimated by HCT-M was higher than that by EMP-M in both groups (P < 0.05). There was a significant difference between group A and group B in blood loss (7.40 ± 1.61 vs 19.91 ± 10.94 ml), operation time (80.51 ± 34.70 vs 136.51 ± 41.88 min), and fluoroscopy frequency (6.92 ± 1.52 vs 11.11 ± 2.32 times) (P < 0.05). The VAS and ODI scores in group B were higher than that in group A 1 week after operation (P < 0.05); however, the scores were not different between the two groups at pre-operation (P > 0.05).ConclusionHCT-M is a reliable method to estimate endoscopic blood loss in PELD. The amount of endoscopic blood loss affects the operative procedure in operation time and fluoroscopy frequency, as well as clinical effects in VAS and ODI scores after operation in short term.
Highlights
Lumbar disk herniation (LDH) is a very common disease in clinical which is associated with both genetic and environmental factors
The amount of endoscopic blood loss affects the operative procedure in operation time and fluoroscopy frequency, as well as clinical effects in visual analog scale (VAS) and Oswestry Disability Index (ODI) scores after operation in short term
The percutaneous endoscopic lumbar discectomy is divided into the posterior approach and the lateral posterior approach [9, 10], whereas the lateral posterior approach is divided into the Yeung endoscopic spine system (YESS) [11] and the transforaminal endoscopic spine system (TESSYS) [12, 13]
Summary
Lumbar disk herniation (LDH) is a very common disease in clinical which is associated with both genetic and environmental factors. The treatment for LDH includes conservative therapy and surgery and the standard open discectomy has largely been replaced by microdiscectomy [1]. According to a Norway longitudinal observation study of 34,639 surgical cases of lumbar disk herniation, microdiscectomy was specified in 23,929 patients (69%) [2]. Percutaneous endoscopic lumbar discectomy (PELD) is one of the microdiscectomy methods which has made significant progress and is well accepted by surgeons in recent years with the development of endoscopic technique and surgical instruments [3, 4]. PELD has become one of the mainstream operative methods for the treatment of LDH [8]. Depending on the segment of disk herniation, the type of disk herniation, and individual surgical habits, the surgeon may perform the endoscopic surgery with different approaches [9, 14,15,16]
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