Abstract

BackgroundCardiovascular disease (CVD) is the largest contributor to the non-communicable diseases (NCD) burden in Cameroon, but data on its economic burden is lacking.MethodsA prevalence-based cost-of-illness study was conducted from a healthcare provider perspective and enrolled patients with ischaemic heart disease (IHD), ischaemic stroke, haemorrhagic stroke and hypertensive heart disease (HHD) from two major hospitals between 2013 and 2017. Determinants of cost were explored using multivariate generalized linear models.ResultsOverall, data from 850 patients: IHD (n = 92, 10.8%), ischaemic stroke (n = 317, 37.3%), haemorrhagic stroke (n = 193, 22.7%) and HHD (n = 248, 29.2%) were analysed. The total cost for these CVDs was XAF 676,694,000 (~US$ 1,224,918). The average annual direct medical costs of care per patient were XAF 1,395,200 (US$ 2400) for IHD, XAF 932,700 (US$ 1600) for ischaemic stroke, XAF 815,400 (US$ 1400) for haemorrhagic stroke, and XAF 384,300 (US$ 700) for HHD. In the fully adjusted models, apart from history of CVD event (β = − 0.429; 95% confidence interval − 0.705, − 0.153) that predicted lower costs in patients with IHD, having of diabetes mellitus predicted higher costs in patients with IHD (β = 0.435; 0.098, 0.772), ischaemic stroke (β = 0.188; 0.052, 0.324) and HHD (β = 0.229; 0.080, 0.378).ConclusionsThis study reveals substantial economic burden due to CVD in Cameroon. Diabetes mellitus was a consistent driver of elevated costs across the CVDs. There is urgent need to invest in cost-effective primary prevention strategies in order to reduce the incidence of CVD and consequent economic burden on a health system already laden with the impact of communicable diseases.

Highlights

  • Cardiovascular disease (CVD) is the largest contributor to the non-communicable diseases (NCD) burden in Cameroon, but data on its economic burden is lacking

  • Prevalent hypertension ranged from 70.7% in those with ischemic heart disease (IHD) to 100% in those with hypertensive heart disease (HHD)

  • The overall prevalence of atrial fibrillation was 9.3%, but this was most common in patients with ischaemic stroke (13.6%) and those with HHD (11%), p < 0.001

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Summary

Introduction

Cardiovascular disease (CVD) is the largest contributor to the non-communicable diseases (NCD) burden in Cameroon, but data on its economic burden is lacking. CVDs are a major cause of hospitalizations globally, with heart failure responsible for about 3 to 7% of hospitalizations in general medical wards [4] and stroke admission rates increasing over five-fold between 1999 and 2012 in Cameroon [5]. These high hospitalization rates likely translate to increased healthcare costs that lead to grim economic consequences on the country, and for a setting without universal health coverage (UHC), this has significant bearing on the affected populations. Authors reported substantial variability across studies, potentially explained by differences in costing perspectives, and CVD costs were several multiples of health expenditure per capita in the majority of LMICs [9]

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