Abstract
Background and objective Anti-inflammatory adipokine Omentin-1 is lately recognized as a novel adipocytokine mainly expressed in visceral fat. Omentin-1 has associations with inflammatory diseases like periodontitis. This research aimed to measure and compare serum and salivary Omentin-1 levels in patients with chronic periodontitis before and after scaling and root planing SRP.Methodology Thirty-five subjects with chronic periodontitis were included in the research. Baseline samples of saliva serum were taken and clinical parameters were recorded following which full mouth SRP was performed. Three months post SRP subjects reported back for the collection of samples as well as the measurement of clinical parameters. The concentration of Omentin-1 in the serum and saliva samples obtained was assessed using an enzyme-linked immunosorbent assay.Results Chronic periodontitis patients had substantially reduced baseline serum and salivary levels of Omentin-1. Clinical parameters showed a substantial decline three months after SRP while the Omentin-1 levels in the serum and saliva significantly increased.Conclusion In chronic periodontitis there is a strong correlation between salivary and serum Omentin-1 levels. As a result the level of Omentin-1 may be utilized as an inflammatory marker of periodontal diseases and to assess the treatment outcome. Keywords Adipokines Chronic Periodontitis Omentin-1 Scaling and root planing
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