Abstract
Background: Information regarding the prognosis and burden of diseases can be used by policymakers to determine competing health priorities. We aimed to assess the Relative Survival Rate (RSR) and loss of expectation of life (LEL) to evaluate the prognosis and burden of diseases in Hemodialysis (HD) patients. Study design: A retrospective cohort study. Methods: We recruited 648 HD patients referred to three referral centers in Kerman City, Iran, from 2008 to 2019. RSR, was defined as the ratio of the observed and the expected survival rates of general population for persons of the same age and sex as patients in the current study. LEL was determined as the difference between corresponding life expectancies (LE). The extended Cox proportional hazard model was used to identify variables associated with the outcome. Results: Variables associated with outcome were diabetic status and age. In the 5th year of the follow-up study, the overall RSR was 0.57. In general, for HD patients, the estimation of LE and LEL was 22.6 and 12.36 year, respectively. Conclusion: HD patients, especially older patients, showed a very poor prognosis, with a large amount of lost life expectancy. Therefore, they need more care and attention from health authorities. It is suggested to estimate the cost of eliminating the risk factors causing kidney diseases.
Highlights
End-stage renal disease (ESRD) is the worst stage of chronic kidney disease (CKD)
It is suggested to estimate the cost of eliminating the risk factors causing kidney diseases
Patient with diabetes and patients who are over 65 yr old had the highest risk of death and the worst prognosis of ESRD
Summary
End-stage renal disease (ESRD) is the worst stage of chronic kidney disease (CKD). Renal replacement therapy (RRT) includes hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation [1, 2]. In Iran, the annual number of patients with ESRD increased by 130% between 2000 and 2006 5, 6. Based on the data available in the 2018 annual report accessible on the US Renal Data System, the crude incidence rate of treated ESRD and the prevalence of treated ESRD were 81 per million probabilities/year and 654 per million population, respectively, in Iran 7. Using 19952013 statistics, the overall trend of survival probabilities in ESRD patients has slightly decreased in Iran 8. About half of the patients with ESRD in Iran are treated with hemodialysis. We aimed to assess the Relative Survival Rate (RSR) and loss of expectation of life (LEL) to evaluate the prognosis and burden of diseases in Hemodialysis (HD) patients
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