Abstract

Exposure of the inhabitants of Najran area in Saudi Arabia to the toxic elements As, Cd, Cr, and Pb through foods has not been previously investigated. Exposure to such elements is an important public health issue, so the study described here was performed with the aim of determining estimated dietary intakes (EDIs) for these metals in Najran area. The As, Cd, Cr, and Pb concentrations in four staple foods (rice, wheat, red meat, and chicken) were determined by inductively coupled plasma-mass spectrometry. A food frequency questionnaire (FFQ) was completed by 80 study participants. These data were used to estimate dietary intakes of the metals in the four staple foods. The mean As, Cd, Cr, and Pb EDIs in the four food types were 1.1 × 10−6–2.6 × 10−5, 1.42 × 10−5–2.2 × 10−4, 3.4 × 10−4–8.0 × 10−4, and 2.3 × 10−5–2.1 × 10−3 mg/kg bw day, respectively. Hazard Quotients (HQ) for all elements did not exceed one. The highest Pb concentration was found for chicken and the source of this toxic element in this food needs to be investigated in the future. The lowest As concentration was found for wheat highest in rice. The EDIs for all elements in the four food types were below the provisional tolerable weekly intakes set by the World Health Organization (WHO).

Highlights

  • Toxic elements are normally found in foodstuffs with various concentrations [1]

  • Of As, Creach fromfood eachclass, foodand class, allclasses food classes combined, thatinvestigated were investigated the current. This is the first study to estimate the dietary intakes of As, Cd, Pb and Cr from main four staple foods that are commonly consumed in a population from Najran city, Kingdom of Saudi Arabia (KSA)

  • The Provisional Tolerable Weekly Intakes (PTWIs) developed by the Joint Food and Agriculture Organization/World Health Organization (WHO) Expert Committee on Food additives is defined as the maximum amount of a contaminant a person can be exposed to per week over a lifetime without posing unacceptable risks to health [30]

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Summary

Introduction

The concentrations of toxic elements in foods depend on the type of food and the route through which the food was exposed to the toxic element. These elements can enter foodstuffs from the environment in different pathways such as contaminated water with untreated municipal, industrial waste and polluted air [2]. Food consumption is considered to be the main pathway, the other pathways being inhalation, dermal contact contaminated water, through which humans are exposed to potentially toxic elements [3,4]. The accumulation of toxic elements including heavy metals such as Cd, Cu, Fe, Mn, Pb and

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